Triclosan can cause cancer? Unresolved

The debate about triclosan is actually an experiment from a teacher at Virginia Tech. It has been found that a product containing triclosan reacts with chlorine-containing tap water to form a substance called "Golofang", which is chloroform. Chloroform has been used as an anesthetic. Animal experiments have found that this substance can cause damage to the heart and liver, has mild teratogenicity, can induce liver cancer in mice, but so far there is no research data on human carcinogenesis.

Ma Yi, secretary-general of the China Daily Miscellaneous Industry Association, said in an interview on the 2nd that it was this research result. As early as 2005, there was a debate about "Triclosan carcinogenicity" at home and abroad. Today, the old story is revisited because the recent US Food and Drug Administration has given the latest assessment of the safety of triclosan. Is triclosan really so terrible? Ma Yi said that the current question about it is still pending.

National standard of toothpaste: no more than 0.3%

Ma Yi said that some experts in the industry have done experiments. The subjects used toothpaste containing triclosan and ordinary chlorinated tap water, and the brushing time exceeded the expected time of ordinary people, but the chloroform content did not reach the measurable range. In the new national standard for toothpaste announced in 2009, triclosan was included in the preservatives allowed to be added, but it should not exceed 0.3%.

Kang Jingwu, director of the analysis department of the Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, said that triclosan is a bacteriostatic agent that can kill bacteria after it is added. Some countries also add to mouthwash and toothpaste. Something like this, some experts say that it is carcinogenic, and now it is said that high doses can cause cancer. The semi-lethal dose of triclosan per kilogram of small mice is 3,800 milligrams. From this point of view, triclosan is not too toxic.

To choose toothpaste, you must first know that toothpaste is not a magic weapon for healthy teeth. It is only an auxiliary accessory for brushing teeth. It has the function of rubbing and removing plaque, cleaning and polishing the tooth surface, and refreshing the mouth. At present, the toothpaste used in China is divided into three categories: ordinary toothpaste, fluoride toothpaste and drug toothpaste.

The main ingredients of ordinary toothpaste include abrasives, cleansers, moisturizers, preservatives, and fragrances. They have the common effect of general toothpaste. If the teeth are in good health, you can choose ordinary toothpaste. However, with the development of science and technology, people have discovered that fluoride can prevent sputum, and it has been proved for many years that fluoride contact with teeth makes the hydroxyapatite which is easily dissolved by acid in the tooth tissue to form insoluble fluorophosphate. Stone, which improves the corrosion resistance of the teeth. Studies have shown that the common incidence of dental caries, the incidence of dental caries decreased by about 40%. Fluoride is sodium fluoride, potassium fluoride, stannous fluoride and sodium monofluorophosphate.

What are the side effects of toothpaste?

However, it is necessary to know that fluorine is a toxic substance. If the body absorbs too much, it will cause fluorosis. According to the state regulations, free fluoride in fluoride toothpaste should be between 400 and 1200 Pm. Special attention should be paid to children before 3-4 years old because 1/8-1/4 of the toothpaste may be swallowed into the stomach. The drug toothpaste is based on the ordinary toothpaste. When the toothpaste is brushed, the toothpaste reaches the surface of the tooth or the environment around the tooth, and the plaque is reduced by the action of the drug, thereby preventing the rickets and periodontal disease.

At present, drug toothpaste is very popular, and it is an ideal way to use toothpaste to promote drugs with preventive or therapeutic effects. But drug toothpaste also has its downsides.

First of all, the toothpaste can not be kept in the mouth for too long, that is, it is thrown out, making it difficult for the drug to exert its efficacy in a short time, and the special drug dosage must also avoid stimulating the soft tissue in the mouth, and thus cannot be increased to a sufficient effective concentration, the toothpaste itself. The effect is often blocked by the dirt in the mouth or limited by the morphological characteristics, so it is difficult to reach the real disease area.

Second, the medicines in toothpaste often have other chemical changes due to long time of storage, and the original effects are lost. The effective drugs are often unsuitable for toothpaste due to odor, and there is also drug resistance. The problem, these factors all indicate that the drug toothpaste is not suitable for long-term use. The drug toothpaste is a good idea, but it is still necessary to do some in-depth research to truly achieve the effect of preventing oral diseases.

Xiaobian tips:

The advertising of toothpaste is overwhelming, especially many drug ointments advertise their therapeutic effects on various oral diseases... Can drug toothpaste really cure dental disease?

Therefore, in the face of many toothpaste varieties, we must first understand the performance of various toothpastes, do not blindly believe in product descriptions, it is best to consult a dental professional to choose the appropriate toothpaste according to the actual situation of your mouth.

(Editor: Xu Xiaoyu)

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